Effect of Pectin and Inulin Fibre Supplementation on Glucose and ANS Modulation
Effect of Pectin and Inulin Fibre Supplementation on Glucose and ANS Modulation
NCT ID: NCT06480799 Phase: NA Status: COMPLETED Enrollment: 30 Completion: 2024-12-31
Conditions
Diet, Healthy, Systemic Inflammatory Response
Interventions
Fibre intervention, Placebo intervention
Summary
The study involves intake of dietary supplements, which are commonly found in the UK diet (not pharmacological agents) to test their effects on inflammation in the body and gut microbiome composition. Study subjects will be healthy volunteers recruited from the University and local population and will be asked to attend the laboratory on 2 occasions; before and after 4-week' supplementing the diet daily with either the dietary fibres (Pectin and Inulin) or placebo (maltodextrin). At each study visit (\~3hrs), participants will be asked to provide a stool and blood sample and will have blood pressure measured. They will also consume a glucose drink to assess how effectively the body regulates its blood glucose concentration. In the week before each study visit, participants will wear an activity and glucose monitor and record their food intake.
Primary Outcome
Change in microbiome profile