Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis
Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis
NCT ID: NCT05758103 Phase: NA Status: COMPLETED Enrollment: 32 Completion: 2022-09-18
Conditions
Peri-implant Mucositis
Interventions
Limosilactobacillus reuteri Prodentis® (combining L. reuteri DSM 17938 and L. reuteri ATCC PTA 5289 strains)
Summary
Mechanical debridement is the traditional method for the treatment of peri-implant mucositis and its success depends on the patient's correct oral hygiene. It is believed that probiotics may help by their ability to modulate the oral biofilm, resulting in anti-inflammatory and anti-bacterial plaque action. The aim of this study is to evaluate the adjuvant effect of the probiotic Limosilactobacillus reuteri in the mechanical treatment of peri-implant mucositis. This study aims to include 32 subjects with implant-supported total rehabilitation and peri-implant mucositis, divided into test and control groups, equally subjected to professional mechanical debridement, with the administration of a daily GUM® PerioBalance® lozenge for 30 days added to the test group. Plaque Index, Bleeding Index and probing pocket depth are evaluated before the intervention (baseline) and at 6 and 10 weeks later.
Primary Outcome
Modified bleeding index