Expression of microRNA-133a and microRNA-208b in Acute Myocardial Infarction
Expression of microRNA-133a and microRNA-208b in Acute Myocardial Infarction
NCT ID: NCT05692752 Phase: Status: COMPLETED Enrollment: 10 Completion: 2023-01-14
Conditions
Myocardial Infarction, Acute
Interventions
No intervention
Summary
Cardiac-enriched micro-RNAs (miRNAs), micro RNA 208b and 133a(MiR-208b, MiR-133a)) corresponds to the health and disorders of the cardiovascular system. An intron of the cardiac myosin heavy chain gene MYH7 encodes miR-208b. It is found on chromosome 14 in humans. Identify new diagnostic biomarkers based on miRNAs, researchers examine the expression of miR-133a and 208b at various time points (04 hours, 08 hours, 12 hours, 24 hours, 48 hours) following the development of the infarct and compared it to the traditional myocardial infarction biomarkers cardiac troponine (cTnl) and Creatine kinase-MB (CK-MB).
Primary Outcome
Expression of miR-133a