Effect of a Probiotic With High Beta-galactosidase Activity on Patients With Lactose Intolerance
Effect of a Probiotic With High Beta-galactosidase Activity on Patients With Lactose Intolerance
NCT ID: NCT05367453 Phase: NA Status: COMPLETED Enrollment: 40 Completion: 2022-02-09
Conditions
Lactose Intolerance
Interventions
Tropical juice with probiotics (B.coagulans), a Tropical juice with no probiotics, lactase tablet, placebo tablet (cornstarch)
Summary
Lactose intolerance is a chronic disease caused by the total/partial lack of lactase production. When lactose is not properly digest, it is consumed by the microbiota. This situation presents different gastrointestinal symptoms such as meteorism, pain, bloating, diarrhoea and nausea. The dietetic treatment for this patients consists of avoiding lactose-rich foods, mainly milk and dairy products. However, nowadays exists a large diversity of lactose-free products specially focused on lactose intolerants. In this context, using B.coagulans as a probiotic in a food matrix could be an alternative for these patients, since its ability of spore forming and the production of beta-galactosidase.
Based on the foregoing, the group research has design a randomized, double-blind, placebo-controlled crossover nutritional clinical trial to evaluate the effect of a regular probiotic with high production of beta-galactosidase effect over gastrointestinal syntoms of patients with lactose intolerance.
Primary Outcome
Gastrointestinal symptoms