Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

NCT ID: NCT05295719 Phase: NA Status: COMPLETED Enrollment: 129 Completion: 2024-12-31

Conditions

Obesity, Inflammation, Human Microbiome, Insulin Resistance, Dyslipidemias

Interventions

Omega-3 polyunsaturated fatty acid, High-Intensity Interval Training, Safflower oil, Low-intensity training

Summary

The goal of this project is to understand the combined effects of fish oil and exercise in obesity-associated inflammation. The investigators hypothesize that fish oil will improve gut bacteria profiles, which will in turn potentiate the benefits of an exercise program and improve energy utilization and reduce inflammation and metabolic risk.

Primary Outcome

Mean Change from Baseline in Serum high-sensitivity C-reactive protein at 4 weeks

Source

ClinicalTrials.gov