Placental Lesions in Fetal Growth Restrictions
Placental Lesions in Fetal Growth Restrictions
NCT ID: NCT04839185 Phase: EARLY_PHASE1 Status: COMPLETED Enrollment: 3 Completion: 2021-10-06
Conditions
Fetal Growth Retardation
Interventions
Ferumoxytol infusion, MRI scan
Summary
The purpose of this research study is to develop imaging methods to diagnose placental injury in pregnancies diagnosed with fetal growth restriction (FGR). Investigators are doing this research because the use of IV iron, followed by a Magnetic resonance imaging (MRI), may help detect injury in the placenta. The IV iron, ferumoxytol, is an iron preparation used for treatment of iron deficiency anemia. It is given in hospital setting under close medical attention. Ferumoxytol(FE) is FDA approved for some uses, but in pregnant women, its use as a MRI contrast is investigational.
Primary Outcome
Number of Participants for Which Intervillous Placental Blood is Detected