Mechanism and Effects of Manipulating Chloride Homeostasis in Stable Heart Failure

NCT ID: NCT03440970 Phase: EARLY_PHASE1 Status: COMPLETED Enrollment: 20 Completion: 2025-08-30

Conditions

Decompensated Heart Failure

Interventions

Lysine Chloride, Placebo

Summary

This study is designed to investigate the quantitative effects of sodium-free chloride supplementation on electrolyte balance, volume status, and sodium avidity in stable heart failure patients in a highly controlled environment.

Primary Outcome

Change in Blood Volume

Source

ClinicalTrials.gov