Nutrition, Arsenic and Cognitive Function in Children
Nutrition, Arsenic and Cognitive Function in Children
NCT ID: NCT03384862 Phase: NA Status: COMPLETED Enrollment: 239 Completion: 2019-05-09
Conditions
Arsenic Exposure
Interventions
Vitamin B12, Placebo, Folic Acid
Summary
The main goals of this study are to evaluate whether supplementation with folate and vitamin B12 to 8 to 10 year old children, in conjunction with reduction in arsenic exposure, can increase arsenic methylation and lower blood arsenic and blood monomethyl arsenic (as previously observed in adults). The investigators will also explore whether folate and B12 can mitigate arsenic-related decrements in cognitive abilities.
Primary Outcome
Change in arsenic methylation