Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression
Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression
NCT ID: NCT03202914 Phase: NA Status: COMPLETED Enrollment: 840 Completion: 2016-01
Conditions
Dietary Modification, Kidney Diseases, Chronic
Interventions
Usual protein and phosphorus diet, Low protein and phosphorus diet, Very low protein and phosphorus
Summary
The present record represents a secondary data analysis of the Modification of Diet in Renal Disease (MDRD) Study. For this analysis, the MDRD study data and specimens were retrieved from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repository. A global, untargeted, metabolomic profile was used to investigate biomarkers of dietary intake as well as biomarkers of kidney disease progression.
Primary Outcome
Serum metabolomic profile