Use of Repetitive Transcranial Magnetic Stimulation to Augment Hypnotic Analgesia
Use of Repetitive Transcranial Magnetic Stimulation to Augment Hypnotic Analgesia
NCT ID: NCT02969707 Phase: NA Status: COMPLETED Enrollment: 101 Completion: 2019-12-21
Conditions
Fibromyalgia
Interventions
MagPro TMS system (MagVenture, Denmark), Hypnosis
Summary
The investigators plan to use functional neuroimaging (fMRI) to understand the brain systems affected when hypnosis and hypnotic analgesia are augmented with repetitive transcranial magnetic stimulation (rTMS), a form of non-invasive brain stimulation to 100 people with fibromyalgia, a chronic pain condition. The investigators will measure the effect of rTMS-augmentation on the brain networks underlying hypnotizability, as well as the effect of rTMS-augmentation on hypnotic analgesia networks. The investigators hope to demonstrate that a combination of these psychological and neuromodulatory treatments will be more effective than hypnosis alone, thereby enhancing the depth of hypnosis, range of hypnosis and the efficacy of hypnotic analgesia and hopefully creating a new treatment modality for individuals suffering from pain syndromes such as fibromyalgia pain.
Primary Outcome
The Change in Functional Connectivity (FC) Between the Left Dorsolateral Prefrontal Cortex (L-DLPFC) and the Dorsal Anterior Cingulate Cortex (dACC)