A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus

NCT ID: NCT02804763 Phase: PHASE2 Status: COMPLETED Enrollment: 182 Completion: 2018-11-19

Conditions

Systemic Lupus Erythematosus (SLE)

Interventions

Placebo, Dapirolizumab pegol (DZP)

Summary

The purpose is to evaluate the efficacy and safety of three different doses of Dapirolizumab Pegol (DZP) versus placebo in adult subjects with moderately to severely active systemic Lupus Erythematosus.

Primary Outcome

Percentage of Participants With British Isles Lupus Assessment Group Disease Activity Index 2004 (BILAG 2004)-Based Composite Lupus Assessment (BICLA) (mNRI) Response Across 3 Doses of Dapirolizumab Pegol (DZP) and Placebo (PBO) at Week 24

Source

ClinicalTrials.gov