Role of 12-lipoxygenase in Platelet Reactivity and Type 2 Diabetes Mellitus
Role of 12-lipoxygenase in Platelet Reactivity and Type 2 Diabetes Mellitus
NCT ID: NCT02629497 Phase: EARLY_PHASE1 Status: COMPLETED Enrollment: 90 Completion: 2017-06
Conditions
Thrombosis, Type 2 Diabetes Mellitus
Interventions
Primrose oil, Fish Oil
Summary
This study investigates the potential protective effects of fatty acid supplementation through inhibition of platelet activation. fatty acids (omega-3 and omega-6) will be evaluated for protection from agonist-mediated platelet activation in platelets from type 2 diabetics and healthy controls. Post-menopausal women with type 2 diabetes mellitus and healthy post-menopausal women will be treated with omega-3 and omega-6 fatty acid supplements to determine protection from platelet activation and thrombosis in this high risk population.
Primary Outcome
platelet reactivity