Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia
Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia
NCT ID: NCT02373579 Phase: PHASE2 Status: COMPLETED Enrollment: 70 Completion: 2014-10
Conditions
Acute Lymphoblastic Leukemia
Interventions
Omega-3 Fatty Acids, Methotrexate
Summary
Study the role of oxidative stress in methotrexate induced hepatic damage, and the possible protective effect of OMEGA-3 fatty acids against methotrexate hepatotoxicity using clinical and biochemical parameters.
Primary Outcome
Number of Participants with Adverse Events as a Measure of Safety and Tolerability by measuring Malondialdehyde (MDA) level changes .