MRI and Microbiota Analysis in Constipation
MRI and Microbiota Analysis in Constipation
NCT ID: NCT02144376 Phase: NA Status: COMPLETED Enrollment: 24 Completion: 2016-06
Conditions
Constipation
Interventions
Ispaghula, Maltodextrin
Summary
The purpose of the study is to test how well magnetic resonance imaging (MRI) can measure whole gut transit time in people with constipation, and how readily it can detect a change in transit time induced by taking a dietary supplement with laxative effects.The investigators expect to demonstrate that ispaghula (psyllium) accelerates movement of matter through the intestinal tract.
The investigators will also assess whether a change in gut bacteria and the chemicals that they release can be detected.
Primary Outcome
Weighted Average Position Score of transit marker capsules as determined by MRI