Glutamine to Improve Outcomes in Cardiac Surgery
Glutamine to Improve Outcomes in Cardiac Surgery
NCT ID: NCT01704430 Phase: NA Status: COMPLETED Enrollment: 60 Completion: 2016-06-21
Conditions
Nosocomial Infection
Interventions
Glutamine, Maltodextrin
Summary
Patients undergoing heart surgery with a heart-lung machine (termed cardiopulmonary bypass) are at an increased risk of having abnormal "inflammation" in their body after surgery. Such inflammation can contribute to slower recovery from surgery, an increased risk of infection, an increased risk of damage to organs other than the heart, and a more complicated course.
Prior research has suggested that using an oral protein supplement made of glutamine (an essential amino acid normally found in your body) can reduce the risk of inflammation, infection and the length of stay in hospital in patients who have suffered major trauma or a burn injury. The investigators believe reducing such inflammation after heart surgery may help promote recovery and reduce the risk of adverse events and complications.
The purpose of this preliminary study is to see if oral glutamine supplementation after heart surgery is practical, and contributes to a reduction in inflammation. The oral glutamine proposed in this study is based on what has been previously studied and what is considered safe.
Primary Outcome
Proportion of Eligible Patients Providing Consent to Participate