The Specific Role of Isoflavones in Reducing Prostate Cancer Risk
The Specific Role of Isoflavones in Reducing Prostate Cancer Risk
NCT ID: NCT00617617 Phase: PHASE2 Status: COMPLETED Enrollment: 52 Completion: 2007-05
Conditions
Prostate Cancer
Interventions
Prevastein HC®, Placebo
Summary
The purpose of this research study is to determine if giving men with early stage (Grade 1-2) prostate cancer dietary supplement from soybeans called isoflavones, will change their blood hormone levels. Isoflavones are substances found in a high concentration in soybeans that are converted in the intestines to hormone-like compounds which are similar to estrogen. They are also thought to have cancer fighting properties. Clinical trials suggest that isoflavones can increase certain sex hormones, which results in the slower production of prostate cancer cells. This study will determine if adding isoflavones (supplied as Prevastein HC®) 80 mg/day in a pill form can change your risk factors that cause early stage prostate cancer to progress to more advanced disease.
Primary Outcome
Observe the effects of the 12 - week intervention with isoflavones on sex hormones and PSA, a marker of disease progression.