Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
NCT ID: NCT00428844 Phase: PHASE2 Status: COMPLETED Enrollment: 75 Completion: 2010-06-23
Conditions
Osteomyelitis
Interventions
daptomycin, daptomycin, vancomycin, teicoplanin, nafcillin, oxacillin, flucloxacillin
Summary
This is a research study designed to look at the efficacy and safety of daptomycin given at a dose of 6 mg/kg or 8 mg/kg in subjects being treated for prosthetic hip or knee infections caused by Staphylococci. These types of bacteria are among the most common types of bacteria causing infections of prosthetic joints.
Primary Outcome
Any Creatine Phosphokinase (CPK) Elevation > 500 Units Per Liter (U/L)