Tyrosine × Levodopa

Severity: MODERATE Evidence: probable

Mechanism

Tyrosine and levodopa compete for the same intestinal absorption transporter.

Effect

Reduced levodopa absorption; worsening Parkinson's symptoms

Management

Separate doses by at least 2 hours.

Source

Glover V et al. J Neural Transm 1980

⚠️ MODERATE INTERACTION: Monitor closely if this combination is used.

Disclaimer

This interaction record is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before starting or stopping any supplement or medication.