Interaction: Red Yeast Rice × Statins
Red Yeast Rice × Statins
Severity: CRITICAL Evidence: well-established
Mechanism
Red yeast rice contains monacolin K (lovastatin). Combined with prescription statins, this doubles statin dose and increases myopathy/rhabdomyolysis risk.
Effect
Additive statin effect; increased myopathy and rhabdomyolysis risk
Management
Avoid combination. Red yeast rice IS a statin — do not combine with prescription statins.
Source
FDA warning; Gordon RY et al. Am J Cardiol 2010
⚠️ CRITICAL INTERACTION: This combination should be AVOIDED.
Disclaimer
This interaction record is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before starting or stopping any supplement or medication.