Omega 3 × Warfarin

Severity: MODERATE Evidence: possible

Mechanism

High-dose omega-3 may reduce platelet aggregation, potentially additive with warfarin.

Effect

Possible increased bleeding risk at high doses (>3g/day)

Management

Monitor INR. Low-dose omega-3 (<1g/day) generally safe.

Source

Buckley MS et al. Ann Pharmacother 2004

⚠️ MODERATE INTERACTION: Monitor closely if this combination is used.

Disclaimer

This interaction record is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before starting or stopping any supplement or medication.