Interaction: Cranberry × Warfarin
Cranberry × Warfarin
Severity: MODERATE Evidence: possible
Mechanism
Cranberry may inhibit CYP2C9, reducing warfarin metabolism. Evidence is conflicting but cases of increased INR exist.
Effect
Possible increased INR and bleeding risk
Management
Monitor INR with cranberry products. Moderate intake is usually safe.
Source
Greenblatt DJ, von Moltke LL. J Clin Pharmacol 2005; Iseme BA et al. Clin Pharmacol Ther 2007
⚠️ MODERATE INTERACTION: Monitor closely if this combination is used.
Disclaimer
This interaction record is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before starting or stopping any supplement or medication.