Coq10 × Warfarin

Severity: MODERATE Evidence: possible

Mechanism

CoQ10 is structurally similar to vitamin K and may reduce warfarin effectiveness.

Effect

Reduced anticoagulant effect; decreased INR

Management

Monitor INR if starting/stopping CoQ10. May need warfarin dose adjustment.

Source

Engelsen J et al. J Am Coll Cardiol 2005

⚠️ MODERATE INTERACTION: Monitor closely if this combination is used.

Disclaimer

This interaction record is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before starting or stopping any supplement or medication.